Table of Contents   This Chapter   All Chapters

INTRODUCTION

Blisters are formed when a potential space within or beneath the epidermis fills with fluid. Depending on the thickness and structural integrity of the blister roof, there may be an obvious tense blister or just an erosion with wrinkled epidermis at the margin. Blisters occur for reasons as trivial as frictional injury, while at the opposite end of the spectrum there are potentially lethal immunobullous disorders and drug-induced blistering. It is therefore important to understand an approach to diagnosis of blistering eruptions.

White/Cox: Diseases of the Skin, 2ed.(c) 2006, Elsevier Inc. All rights reserved.